OMIP COLLECTION
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CD4 and CD8 positive T cells are the major T cell subpopulations in our adaptive immune system. CD4 positive T cells function as "helper cells". CD8 positive T cells are usually called cytotoxic T cells, functioning to directly kill virus-infected cells and cancer center.
B cells are antibody-producing cells in the humoral immunity component of the adaptive immune system.
NK cells is a type of cytotoxic lymphocyte in our innate immune system. It can provide rapid responses to virus-infected cells and tumor cells.
Dendritic cells are antigen-presenting cells (APCs), functioning is to process antigen and present it on the cell surface to the T cells. Therefore, they are messengers between the innate and the adaptive immune systems.
Treg is a type of suppressor T cell. It regulates immune system by maintaining body's tolerance to self-antigens, and prevent autoimmune disease.
Innate lymphoid cell is a type of innate immune cells that has been recently discovered. ILCs are primarily tissue resident cells, particularly abundant at mucosal surfaces, and rarely in the peripheral blood.
Other hematopoietic and immune cells covered by OMIPs include mucosal-associated invariant T (MAIT) cells, natural Killer T (NKT) cells, gamma-delta T cells, monocyte, neutrophils, eosinophils, basophils, hematopoietic stem and progenitor cells.
tissue derived cells covered by OMIPs include prostate-derived cells and microglial cell from brain.